Santa Cruz Tlaxcala Vacations from $186

Book a Hotel + Flight or Car together to unlock savings

The Latest Santa Cruz Tlaxcala vacation packages

Price found within the past 48 hours. Click for updated prices.
Capital O Hotel Emperadores Inn, Atlixco

Capital O Hotel Emperadores Inn, Atlixco

Save 100% on your flight
$186
per person
Nov 17 - Nov 21
found 3 hours ago
Roundtrip flight included
Guadalajara (GDL) to Puebla (PBC)
7/10 Good! (238 reviews)
Molino de los Reyes

Molino de los Reyes

Save 100% on your flight
$748
per person
Nov 19 - Nov 26
found 1 day ago
Roundtrip flight included
Houston (IAH) to Puebla (PBC)
9/10 Wonderful! (14 reviews)
Casona María

Casona María

Puebla Historic Center
Save 100% on your flight
$422
per person
Nov 17 - Nov 21
found 1 day ago
Roundtrip flight included
Guadalajara (GDL) to Puebla (PBC)
9.4/10 Exceptional! (506 reviews)
Es un hotel chiquito por lo que en la mañana se escucha absolutamente todo el ruido de todo, nos tocó una habitación casi en la entrada del hotel, así que imposible levantarte tarde porque hacen mucho ruido. Las almohadas y el colchón son durísimos, así que tampoco descansamos bien, nos levantamos adoloridos. En el checkout mi esposo comentó eso y le dijeron que había un "menú de almohadas", el cual no teníamos idea de que existía y por supuesto que al hacer checkout ya no nos sirve de nada la información. Quizás si nos hubieran informado eso al checkin, pero en lugar de decirnos lo que incluía nuestra tarifa, los servicios, etc., en recepción nos hicieron firmar un aviso de privacidad (para enviar publicidad) y a firmar un reglamento, y nos explicaron que no podíamos ensuciar las toallas, no podíamos ensuciar no se que, que había artesanías en el cuarto y no podíamos romperlas (ni supe cuales artesanías), que no podíamos hacer mucho ruido, en fin.... nos leyó la cartilla con todo lo que estaba prohibido hacer y justo se le olvidó decirnos lo que sí podíamos. De verdad tenía miedo de usar las toallas, casi casi que mejor dormía afuera para no ensuciarle la habitación, jajajajaja. Y en general, el staff eran como malencarados, no muy "amables" o sonrientes, como que todo les pesaba, igual fue en el desayuno. En fin. El lugar es lindo, pero el servicio no.

Reviewed on Sep 30, 2026

Gamma Puebla Señorial Centro

Gamma Puebla Señorial Centro

Puebla Historic Center
Save 100% on your flight
$426
per person
Nov 17 - Nov 21
found 1 day ago
Roundtrip flight included
Guadalajara (GDL) to Puebla (PBC)
8.4/10 Very Good! (1,002 reviews)
Capital O Hotel Boutique Las Torres

Capital O Hotel Boutique Las Torres

Save 100% on your flight
$432
per person
Nov 19 - Nov 26
found 1 day ago
Roundtrip flight included
Houston (IAH) to Puebla (PBC)
9.2/10 Wonderful! (88 reviews)
Friendly staff

Reviewed on Jul 11, 2026

Don't see what you're looking for?
See all available trips from Columbus to Santa Cruz Tlaxcala
View all trips

Santa Cruz Tlaxcala Hotel Deals

Centro Vacacional La Trinidad

Centro Vacacional La Trinidad

s/n Del Trabajo Santa Cruz Tlaxcala TLAX
$39 nightly
$46 total
Oct 11 - Oct 12
Total with taxes and fees
6.8/10 (10 reviews)
"Overall, the property is old, the room was little bit dirty, front desk very rude, the rest were very kind."

Reviewed on Apr 28, 2026

Centro Vacacional La Trinidad
Fiesta Inn Parque Puebla

Fiesta Inn Parque Puebla

Calzada Ignacio Zaragoza, Número 410 Puebla PUE
Fully refundableReserve now, pay when you stay
$76 nightly
$90 total
Nov 2 - Nov 3
Total with taxes and fees
9.4/10 Exceptional! (991 reviews)
"Friendly staff ,super clean , always helpful"

Reviewed on Oct 2, 2026

Fiesta Inn Parque Puebla
Marriott Puebla Hotel Meson del Angel

Marriott Puebla Hotel Meson del Angel

Avenida Hermanos Serdan 807 Puebla PUE
Fully refundableReserve now, pay when you stay
$63 nightly
$75 total
Oct 11 - Oct 12
Total with taxes and fees
Marriott Puebla Hotel Meson del Angel
See all 258 properties in Santa Cruz Tlaxcala
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santa Cruz Tlaxcala Vacation Packages

Santa Cruz Tlaxcala Essential Information

More vacations you might like

Frequently asked questions

How much does a Santa Cruz Tlaxcala vacation package cost?
You'll find cheap prices from $186 on Expedia for your Santa Cruz Tlaxcala getaway. However, a range of factors like the hotel choice, length of stay and season will determine how much your vacation to Santa Cruz Tlaxcala costs.
What are the cheapest months to go to Santa Cruz Tlaxcala?
You're likely to find lower rates and better availability in January, May and June. Take a look at our cheap Santa Cruz Tlaxcala vacation packages and you could get some excellent off-season deals.
How many days is enough for Santa Cruz Tlaxcala?
With a well-organized itinerary, you can easily visit the main Santa Cruz Tlaxcala sights in a few days. But if you'd like to discover lesser-known spots or go on day tours, consider booking your Santa Cruz Tlaxcala vacation for longer.
How to find the best Santa Cruz Tlaxcala package deals?
Landing a cheap Santa Cruz Tlaxcala package deal is easy with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply a couple of filters and see what's available. You can fine-tune your search by "Popular locations," "Property type," "Guest rating" and more. Order the results by "Price: low to high" to view the most affordable Santa Cruz Tlaxcala package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santa Cruz Tlaxcala vacation as a package?
Expedia vacation packages are designed to help you keep more money in your pocket. Bundle your hotel, flight and car rental into one great-value price and you could save hundreds of dollars. You'll typically score a better deal than booking each component individually. And you'll still get the flexibility to create a customized Santa Cruz Tlaxcala vacation by choosing your favorite accommodation type, airline and car class.
When to book a vacation package to Santa Cruz Tlaxcala?
If you're planning a spur-of-the-moment Santa Cruz Tlaxcala adventure, check out our last-minute deals that can be booked up to a week before you go. Prefer not to wait until the last minute? You can find terrific deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santa Cruz Tlaxcala vacation packages?
Your Santa Cruz Tlaxcala break should be an escape from your daily routine, not a reason for money worries. So to give you a bit more flexibility, we've partnered with online lender Affirm to offer our Book Now, Pay Later vacations. Choose one of our vacation packages with payment plans and spread the cost over 3, 6 or 12 months. Plus, there aren't any hidden or late payment fees to worry about.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.